Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723057 | 0.83 | MEN1 (0.43) | MEN1KMT2AMAPTTDP1PTPN2 | |
| Potassium Ion SCHEMBL11502616 | 0.80 | ALDH1A1 (0.34) | MEN1KMT2AMAPTTDP1PTPN2 | |
| Hydrochloric Acid SCHEMBL11502756 | 0.80 | ACLY (0.42) | MEN1KMT2AMAPTTDP1PTPN2 | |
| SCHEMBL17927701 | 0.77 | KMT2A (0.50) | MEN1KMT2ATDP1POLBALDH1A1 | |
| SCHEMBL7475833 | 0.73 | RAB9A (0.59) | MEN1KMT2AMAPTTDP1POLB | |
| SCHEMBL11547437 | 0.71 | LMNA (0.32) | KMT2ALMNANPSR1 | |
| SCHEMBL11506417 | 0.71 | PTGDR2 (0.39) | MEN1KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL15276735 | 0.70 | MEN1 (0.50) | MEN1KMT2AMAPTTDP1PTPN2 | |
| SCHEMBL3059991 | 0.70 | POLB (0.34) | POLBLMNACA1CA2MMP1 | |
| SCHEMBL27402677 | 0.70 | ALDH1A1 (0.38) | MEN1KMT2AMAPTTDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001113-A1 | Thienothiazine derivatives, their preparation and compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-03-21 | — | — | EP | disclosed |
| US-4028373-A | ARTIFICIAL SWEETNERS | BASF AKTIENGESELLSCHAFT (DT) | 1977-06-07 | — | — | US | disclosed |