Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.64 |
| ▸ | CNR2 | P34972 | 2/20 | 0.64 |
| ▸ | ESR1 | P03372 | 14/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592398 | 0.95 | CNR1 (0.70) | CNR1CNR2ESR1ESR2MEN1 | |
| SCHEMBL11552702 | 0.94 | CNR1 (0.64) | CNR1CNR2ESR1ESR2MEN1 | |
| SCHEMBL7107598 | 0.90 | ESR1 (0.75) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL11554603 | 0.89 | ESR1 (0.64) | CNR1CNR2ESR1ESR2 | |
| SCHEMBL11548713 | 0.89 | CNR1 (0.62) | CNR1CNR2ESR1ESR2MEN1 | |
| SCHEMBL11732074 | 0.86 | ESR1 (0.62) | CNR1CNR2ESR1ESR2MEN1 | |
| SCHEMBL6595048 | 0.85 | CNR2 (0.90) | CNR1CNR2ESR1ESR2TDP1 | |
| SCHEMBL7411734 | 0.85 | CNR2 (0.90) | CNR1CNR2ESR1ESR2TDP1 | |
| SCHEMBL11547729 | 0.85 | ESR1 (0.68) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL11548512 | 0.84 | CNR1 (0.71) | CNR1CNR2ESR1ESR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |