Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 16/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107598 | 0.95 | ESR1 (0.75) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL11552368 | 0.95 | ESR1 (0.75) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL1665657 | 0.88 | ESR1 (0.86) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL11550840 | 0.87 | CNR1 (0.71) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL11552941 | 0.87 | CNR1 (0.71) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL11547449 | 0.85 | CNR1 (0.64) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL11552702 | 0.85 | CNR1 (0.64) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL11546633 | 0.84 | ESR1 (0.67) | ESR1ESR2MEN1KMT2ATDP1 | |
| SCHEMBL11546554 | 0.82 | CNR1 (0.67) | ESR1ESR2TDP1 | |
| SCHEMBL11551107 | 0.82 | CNR1 (0.67) | ESR1ESR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |