Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.54 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25984793 | 0.82 | HSD11B1 (0.81) | HSD11B1TAS2R14ALDH1A1POLBCNR2 | |
| SCHEMBL6830704 | 0.80 | CNR2 (0.50) | HSD11B1TAS2R14RECQLALDH1A1POLB | |
| SCHEMBL11582455 | 0.79 | HSD11B1 (0.81) | HSD11B1TAS2R14RECQLALDH1A1KEAP1 | |
| SCHEMBL6803488 | 0.76 | LIMK2 (0.49) | HSD11B1TAS2R14ALDH1A1POLBTP53 | |
| SCHEMBL6803486 | 0.75 | TP53 (0.47) | HSD11B1TAS2R14ALDH1A1POLBTP53 | |
| SCHEMBL31455542 | 0.75 | HSD11B1 (0.64) | HSD11B1TAS2R14ALDH1A1POLBTP53 | |
| SCHEMBL25349817 | 0.74 | TP53 (0.69) | HSD11B1ALDH1A1KDM4ETP53CA12 | |
| SCHEMBL25434133 | 0.74 | HSD11B1 (0.53) | HSD11B1TAS2R14RECQLALDH1A1KEAP1 | |
| SCHEMBL9789406 | 0.73 | HSD11B1 (0.51) | HSD11B1TAS2R14ALDH1A1KEAP1NFE2L2 | |
| SCHEMBL25437664 | 0.72 | HSD11B1 (0.51) | HSD11B1TAS2R14RECQLALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157257-A | HERBICIDES FOR APPLICATION TO AQUATIC RICE PADDIES | UTSUNOMIYA UNIVERSITY (JP) | 1979-06-05 | — | — | US | disclosed |