Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537188 | 0.79 | KDM4E (0.41) | KDM4EGAAARALDH1A1MAOA | |
| SCHEMBL11537303 | 0.75 | PSMB5 (0.62) | KDM4EGAAARCA1CA12 | |
| SCHEMBL29373878 | 0.72 | KDM4E (0.71) | KDM4EGAAARCA1CA12 | |
| SCHEMBL1137861 | 0.71 | MAPT (0.47) | KDM4EGAAARCA1CA7 | |
| SCHEMBL1922596 | 0.70 | KDM4E (0.55) | KDM4EGAAARCA1CA7 | |
| SCHEMBL14284005 | 0.68 | KDM4E (0.47) | KDM4EGAACA1MAPTCYP3A4 | |
| SCHEMBL1429171 | 0.68 | KDM4E (0.63) | KDM4EGAACA12CA7MAPT | |
| SCHEMBL69925 | 0.67 | TDP1 (0.52) | KDM4EGAACA1CA12CA7 | |
| SCHEMBL29403778 | 0.67 | TDP1 (0.52) | KDM4EGAACA1CA12CA7 | |
| SCHEMBL13835746 | 0.66 | KDM4E (0.52) | KDM4ECA1CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000482-A1 | Process for the preparation of 8-methoxypsorales and intermediates in this preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-02-07 | — | — | EP | disclosed |