Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12316566 | 0.83 | MAPT (0.51) | KDM4EHSD17B10MAPTCASP1CASP7 | |
| SCHEMBL31411168 | 0.83 | MAPT (0.51) | KDM4EHSD17B10MAPTCASP1CASP7 | |
| SCHEMBL3411326 | 0.81 | MAPT (0.42) | KDM4EHSD17B10MAPTCASP1CASP7 | |
| SCHEMBL2496128 | 0.81 | KDM4E (0.42) | KDM4EHSD17B10MAPTCASP1CASP7 | |
| SCHEMBL9372790 | 0.79 | AR (0.47) | KDM4EHSD17B10MAPTCASP1CASP7 | |
| SCHEMBL1029836 | 0.78 | KDM4E (0.67) | KDM4EHSD17B10MAPTCASP1CASP7 | |
| SCHEMBL18416056 | 0.77 | MAPT (0.38) | KDM4EHSD17B10MAPTCASP1CASP7 | |
| SCHEMBL1922629 | 0.76 | NR3C1 (0.44) | KDM4EHSD17B10MAPTCASP1CASP7 | |
| SCHEMBL1922630 | 0.76 | NR3C1 (0.44) | KDM4EHSD17B10MAPTCASP1CASP7 | |
| SCHEMBL26728820 | 0.76 | KDM4E (0.48) | KDM4EHSD17B10MAPTCASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092034-A1 | 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME | KULEON LLC (US) | 2026-04-02 | — | — | US | disclosed |
| US-20250340513-A1 | NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS | KULEON LLC (US) | 2025-11-06 | — | — | US | disclosed |
| US-12441683-B2 | 7-methyl indole analogs and dosage forms containing the same | Kuleon, LLC (US) | 2025-10-14 | — | — | US | disclosed |
| US-20250282722-A1 | 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME | KULEON LLC (US) | 2025-09-11 | — | — | US | disclosed |
| US-12344582-B2 | Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression | Kuleon, LLC (US) | 2025-07-01 | — | — | US | disclosed |
| US-20250122213-A1 | OPIOID RECEPTOR MODULATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-04-17 | — | — | US | disclosed |
| US-12275701-B2 | Neuroplastogens and non-hallucinogenic serotonin 5-HT2A receptor modulators | Kuleon, LLC (US) | 2025-04-15 | — | — | US | disclosed |
| US-20250091991-A1 | MIXED SEROTONIN 5-HT2A/2C RECEPTOR AGONISTS AND METHODS FOR TREATING PAIN AND DEPRESSION | Kuleon, LLC (US) | 2025-03-20 | — | — | US | disclosed |
| US-12195478-B2 | Opioid receptor modulators | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-01-14 | — | — | US | disclosed |
| EP-4487913-A2 | OPIOID RECEPTOR MODULATORS | The Trustees Of Columbia University In The City Of New York (US) | 2025-01-08 | — | — | EP | disclosed |
| WO-2009109502-A1 | 2-AMINOQUINOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109491-A1 | 2-AMINOQUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-11 | — | — | WO | disclosed |
| US-20090227583-A1 | 2-AMINOQUINOLINES | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2009-09-10 | — | — | US | disclosed |
| US-20090227584-A1 | 2-AMINOQUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-10 | — | — | US | disclosed |
| US-20090227570-A1 | 2-AMINOQUINOLINES | HOFFMANN-LA ROCHE, INC. | 2009-09-10 | — | — | US | disclosed |
| US-20020086895-A1 | Methods of treating fungal infections | CHU WAI-LAM ALEX (US) | 2002-07-04 | — | — | US | disclosed |
| EP-1005338-A4 | SUBSTITUTED AURONE DERIVATIVES | PHYTERA INC (US) | 2001-11-07 | — | — | EP | disclosed |
| US-6307070-B1 | FUNGICIDES | PHYTERA, INC. | 2001-10-23 | — | — | US | disclosed |
| EP-1005338-A1 | SUBSTITUTED AURONE DERIVATIVES | PHYTERA, INC. (US) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999004789-A1 | SUBSTITUTED AURONE DERIVATIVES | PHYTERA, INC. (US) | 1999-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092034-A1 | 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME | HTR2C, HTR7, HTR6 | KDM4E 2618/4885HSD17B10 1289/4885MAPT 3403/4885 |
| US-20090227583-A1 | 2-AMINOQUINOLINES | HTR5A, HTR2C, HTR2B | KDM4E 1411/4885HSD17B10 3125/4885MAPT 905/4885 |
| US-20250282722-A1 | 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME | HTR7, HTR2C, HTR1A | KDM4E 971/4885HSD17B10 2728/4885MAPT 1778/4885 |
| US-12195478-B2 | Opioid receptor modulators | OPRM1, OPRL1, OPRD1 | KDM4E 1372/4885HSD17B10 1565/4885MAPT 3739/4885 |
| US-20020086895-A1 | Methods of treating fungal infections | COXFA4L2, DPM1, ERG28 | KDM4E 2808/4885HSD17B10 880/4885MAPT 3552/4885 |
| US-20090227584-A1 | 2-AMINOQUINOLINE DERIVATIVES | HTR5A, HTR2C, HTR2B | KDM4E 1083/4885HSD17B10 2903/4885MAPT 947/4885 |
| US-12441683-B2 | 7-methyl indole analogs and dosage forms containing the same | HTR7, HTR2C, HTR1A | KDM4E 971/4885HSD17B10 2728/4885MAPT 1778/4885 |
| US-12275701-B2 | Neuroplastogens and non-hallucinogenic serotonin 5-HT2A receptor modulators | HTR2A, HTR2C, HTR1A | KDM4E 2400/4885HSD17B10 3899/4885MAPT 2422/4885 |
| US-20250122213-A1 | OPIOID RECEPTOR MODULATORS | OPRM1, OPRL1, OPRD1 | KDM4E 1372/4885HSD17B10 1565/4885MAPT 3739/4885 |
| US-20250340513-A1 | NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS | HTR2A, HTR2C, HTR3A | KDM4E 2187/4885HSD17B10 3877/4885MAPT 2985/4885 |
| US-20090227570-A1 | 2-AMINOQUINOLINES | HTR5A, HTR2C, HTR2A | KDM4E 1399/4885HSD17B10 3340/4885MAPT 2836/4885 |
| US-12344582-B2 | Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression | HTR2A, HTR2C, HTR3A | KDM4E 3759/4885HSD17B10 2853/4885MAPT 3756/4885 |
| US-20250091991-A1 | MIXED SEROTONIN 5-HT2A/2C RECEPTOR AGONISTS AND METHODS FOR TREATING PAIN AND DEPRESSION | HTR2A, HTR2C, HTR3A | KDM4E 3759/4885HSD17B10 2853/4885MAPT 3756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.