Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 5/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.43 |
| ▸ | CBR1 | P16152 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11492598 | 0.90 | FFAR1 (0.47) | FFAR1TTRMRGPRX4SLC6A2SLC6A3 | |
| SCHEMBL11540799 | 0.86 | SCN9A (0.45) | SLC6A2SLC6A3SLC6A4MAPTHPGD | |
| SCHEMBL11492112 | 0.84 | FFAR1 (0.44) | FFAR1TTRMRGPRX4SLC6A2SLC6A3 | |
| SCHEMBL11492114 | 0.84 | FFAR1 (0.44) | FFAR1TTRMRGPRX4SLC6A2SLC6A3 | |
| SCHEMBL11487620 | 0.82 | FFAR1 (0.48) | FFAR1TTRMRGPRX4SLC6A2SLC6A3 | |
| SCHEMBL11487617 | 0.82 | FFAR1 (0.48) | FFAR1TTRMRGPRX4SLC6A2SLC6A3 | |
| SCHEMBL11487119 | 0.81 | CYP1A2 (0.44) | FFAR1MAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL11487122 | 0.81 | CYP1A2 (0.44) | FFAR1MAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL11486101 | 0.80 | KMT2A (0.45) | FFAR1MAPTHPGDLMNAMEN1 | |
| SCHEMBL11490386 | 0.80 | KMT2A (0.45) | FFAR1MAPTHPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151302-A | Araliphatic dihalogen compounds composition and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |
| US-4057647-A | Araliphatic dihalogen compounds and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-11-08 | — | — | US | disclosed |