Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 9/20 | 0.45 |
| ▸ | FPR2 | P25090 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547652 | 0.86 | FFAR1 (0.48) | SLC6A4KCNH2SLC6A2SLC6A3MAPT | |
| SCHEMBL11543678 | 0.86 | HSPB1 (0.46) | SLC6A4KCNH2HTR2A | |
| SCHEMBL11544485 | 0.81 | SCN9A (0.46) | SCN9AFPR2SMN1; SMN2PTGER4IGFBP3 | |
| SCHEMBL756150 | 0.79 | MAPT (0.53) | SCN9AFPR2MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11540797 | 0.79 | SCN9A (0.46) | SCN9AFPR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11545459 | 0.78 | F2 (0.43) | SCN9AFPR2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11492598 | 0.77 | FFAR1 (0.47) | SLC6A4KCNH2SLC6A2SLC6A3MAPT | |
| SCHEMBL11491850 | 0.77 | HSPB1 (0.45) | SLC6A4KCNH2SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL753409 | 0.77 | SCN9A (0.44) | SCN9AFPR2SLC6A4KCNH2SLC6A2 | |
| SCHEMBL2544053 | 0.77 | SCN9A (0.44) | SCN9AFPR2SLC6A4KCNH2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151302-A | Araliphatic dihalogen compounds composition and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |
| US-4057647-A | Araliphatic dihalogen compounds and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-11-08 | — | — | US | disclosed |