Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | GPR3 | P46089 | 1/20 | 0.57 |
| ▸ | PTPRC | P08575 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1152020 | 0.92 | CHEK1 (1.00) | CHEK1KMT2AMEN1L3MBTL1PTPRC | |
| SCHEMBL29789038 | 0.91 | CHEK1 (0.69) | CHEK1KMT2AMEN1L3MBTL1PTPRC | |
| SCHEMBL2706112 | 0.91 | CHEK1 (0.69) | CHEK1KMT2AMEN1L3MBTL1PTPRC | |
| SCHEMBL11667243 | 0.90 | CHEK1 (0.97) | CHEK1KMT2AMEN1L3MBTL1PTPRC | |
| SCHEMBL11558567 | 0.89 | CHEK1 (0.69) | CHEK1KMT2AMEN1L3MBTL1GPR3 | |
| SCHEMBL31365268 | 0.87 | CHEK1 (0.65) | CHEK1KMT2AMEN1L3MBTL1PTPRC | |
| Monoethanolamine SCHEMBL11634327 | 0.83 | CHEK1 (0.82) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL14199812 | 0.81 | CHEK1 (0.84) | CHEK1KMT2AMEN1L3MBTL1PTPRC | |
| SCHEMBL11632576 | 0.81 | CHEK1 (0.82) | CHEK1KMT2AMEN1L3MBTL1PTPRC | |
| SCHEMBL5798092 | 0.80 | CHEK1 (0.78) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177257-A | ANTIANAPHYLACTIC AGENTS | BURROUGHS WELLCOME CO. (US) | 1979-12-04 | — | — | US | disclosed |
| US-4145350-A | ANTIALLERGENS, TETRAZOLYL- SUBSTITUTED | BURROUGHS WELLCOME CO. (US) | 1979-03-20 | — | — | US | disclosed |