Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PTPRC | P08575 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10626360 | 0.93 | CHEK1 (0.79) | CHEK1KMT2AMEN1L3MBTL1TTR | |
| SCHEMBL1152020 | 0.92 | CHEK1 (1.00) | CHEK1KMT2AMEN1L3MBTL1TTR | |
| SCHEMBL11667243 | 0.90 | CHEK1 (0.97) | CHEK1KMT2AMEN1L3MBTL1TTR | |
| SCHEMBL2706112 | 0.90 | CHEK1 (0.69) | CHEK1KMT2AMEN1L3MBTL1TTR | |
| SCHEMBL29789038 | 0.90 | CHEK1 (0.69) | CHEK1KMT2AMEN1L3MBTL1TTR | |
| SCHEMBL31365268 | 0.86 | CHEK1 (0.65) | CHEK1KMT2AMEN1L3MBTL1TTR | |
| SCHEMBL11629994 | 0.86 | CHEK1 (0.69) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL11633736 | 0.86 | CHEK1 (0.69) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL10625641 | 0.86 | CHEK1 (0.69) | CHEK1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL11636020 | 0.85 | CHEK1 (0.68) | CHEK1KMT2AMEN1L3MBTL1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351461-B2 | Articles comprising benzopyran colorants, method of manufacture, and method of use | GENERAL ELECTRIC COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| US-20070238817-A1 | Articles Comprising Benzopyran Colorants, Method Of Manufacture, And Method Of Use | GENERAL ELECTRIC COMPANY (US) | 2007-10-11 | — | — | US | disclosed |
| US-7270772-B2 | Benzopyran colorants, method of manufacture, and method of use | GENERAL ELECTRIC COMPANY (US) | 2007-09-18 | — | — | US | disclosed |
| US-20070122746-A1 | BENZOPYRAN COLORANTS, METHOD OF MANUFACTURE, AND METHOD OF USE | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070122746-A1 | BENZOPYRAN COLORANTS, METHOD OF MANUFACTURE, AND METHOD OF USE | CBR3, CBR1, NQO1 | CHEK1 2089/4885KMT2A 3492/4885MEN1 1330/4885 |
| US-20070238817-A1 | Articles Comprising Benzopyran Colorants, Method Of Manufacture, And Method Of Use | CBR3, CBR1, HCCS | CHEK1 2050/4885KMT2A 3462/4885MEN1 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.