Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953936 | 0.98 | THRB (0.33) | THRB | |
| SCHEMBL1406214 | 0.92 | THRB (0.37) | THRB | |
| SCHEMBL38660714 | 0.90 | THRB (0.40) | THRB | |
| Fluoride SCHEMBL8466578 | 0.87 | TP53 (0.32) | — | |
| Fluoride SCHEMBL10485893 | 0.84 | CYP1A2 (0.30) | — | |
| SCHEMBL9491565 | 0.81 | — | — | |
| SCHEMBL1681705 | 0.80 | — | — | |
| SCHEMBL1134099 | 0.79 | — | — | |
| Fluoride SCHEMBL8463241 | 0.78 | TP53 (0.35) | — | |
| SCHEMBL20564554 | 0.75 | TP53 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136121-A | PROCESS FOR THE PREPARATION OF FLUORINE-CONTAINING KETONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-23 | — | — | US | disclosed |