Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 4/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976923 | 0.78 | DDB1 (0.47) | DDB1CRBNCTRB1CFTRGOPC | |
| SCHEMBL16800807 | 0.76 | TP53 (0.40) | TP53HTR2B | |
| SCHEMBL11548049 | 0.74 | DDB1 (0.47) | DDB1CRBNCTRB1CFTRGOPC | |
| SCHEMBL13210441 | 0.71 | DDB1 (0.57) | DDB1CRBNCTRB1CFTRGOPC | |
| SCHEMBL24102958 | 0.67 | DDB1 (0.43) | DDB1CRBNCTRB1CFTRGOPC | |
| SCHEMBL3534373 | 0.67 | DDB1 (0.47) | DDB1CRBNCTRB1CFTRGOPC | |
| SCHEMBL12539690 | 0.66 | CFTR (0.69) | DDB1CRBNCTRB1CFTRGOPC | |
| SCHEMBL29161356 | 0.66 | DDB1 (0.46) | DDB1CRBNCTRB1CFTRGOPC | |
| SCHEMBL1751794 | 0.65 | DDB1 (0.50) | DDB1CRBNCTRB1CFTRGOPC | |
| SCHEMBL876859 | 0.65 | TP53 (0.44) | DDB1CRBNCTRB1CFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003738-A1 | Process for producing cyclohexane-1,3-diones or 3-alkoxy-2-cyclohexenones | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1979-09-05 | — | — | EP | disclosed |