Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.44 |
| ▸ | KDM4A | O75164 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.44 |
| ▸ | TET3 | O43151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945134 | 0.90 | LMNA (0.52) | LMNASLC22A6FOLH1TSHRNFKB1 | |
| SCHEMBL11600199 | 0.86 | LMNA (0.53) | LMNASLC22A6FOLH1CYP1A2GABRP | |
| SCHEMBL321084 | 0.86 | AKR1B1 (0.50) | SLC22A6TSHR | |
| SCHEMBL28105796 | 0.83 | FFAR4 (0.58) | SLC22A6TSHR | |
| SCHEMBL8011806 | 0.83 | FFAR4 (0.58) | SLC22A6TSHR | |
| SCHEMBL6120289 | 0.83 | FFAR4 (0.58) | SLC22A6TSHR | |
| SCHEMBL5729462 | 0.81 | — | — | |
| SCHEMBL7365577 | 0.80 | HDAC1 (0.48) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL7352946 | 0.80 | LMNA (0.46) | LMNASLC22A6FOLH1CYP1A2GABRP | |
| SCHEMBL7149918 | 0.79 | FOLH1 (0.52) | TET2KDM4AKDM4CKDM2ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179507-A | NEUROMUSCULAR PARALYSIS, MUSCLE RELAXANTS, ISOQUINOLINE DERIVATIVES | BURROUGHS WELLCOME CO. (US) | 1979-12-18 | — | — | US | disclosed |