Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551934 | 0.97 | MAPK1 (0.48) | MAPK1L3MBTL1LMNAHCRTR1HCRTR2 | |
| SCHEMBL11553668 | 0.95 | MAPK1 (0.45) | MAPK1L3MBTL1LMNAHCRTR1HCRTR2 | |
| SCHEMBL11545551 | 0.92 | MAPK1 (0.45) | MAPK1L3MBTL1LMNAHCRTR1HCRTR2 | |
| SCHEMBL11547399 | 0.90 | MAOB (0.44) | MAPK1L3MBTL1LMNAHCRTR1HCRTR2 | |
| SCHEMBL11550006 | 0.88 | KMT2A (0.45) | MAPK1L3MBTL1LMNAALDH1A1KDM4E | |
| SCHEMBL11552086 | 0.88 | LMNA (0.44) | MAPK1L3MBTL1LMNAKMT2AGAA | |
| SCHEMBL11550248 | 0.87 | LMNA (0.44) | MAPK1L3MBTL1LMNAHCRTR1HCRTR2 | |
| SCHEMBL11553774 | 0.86 | LMNA (0.46) | MAPK1L3MBTL1LMNAHCRTR1HCRTR2 | |
| SCHEMBL11554068 | 0.86 | PTPN11 (0.47) | MAPK1L3MBTL1LMNATSHR | |
| SCHEMBL11547207 | 0.85 | SLC22A12 (0.47) | MAPK1HPGDALDH1A1KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |