Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCD | Q05655 | 3/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 3/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.33 |
| ▸ | PRKACA | P17612 | 2/20 | 0.33 |
| ▸ | CLK2 | P49760 | 2/20 | 0.33 |
| ▸ | PRKX | P51817 | 2/20 | 0.33 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490706 | 0.75 | HPGD (0.45) | SSTR4SMN1; SMN2 | |
| SCHEMBL19416375 | 0.74 | TSHR (0.35) | PRKCDPRKCHPRKCEPRKCQTAAR1 | |
| SCHEMBL17171588 | 0.74 | NOS3 (0.45) | PRKCDPRKCHPRKCEPRKCQTAAR1 | |
| SCHEMBL3528380 | 0.69 | KDM4E (0.55) | TAAR1KDM4EMAP4K4P2RX7MAPK1 | |
| SCHEMBL422296 | 0.69 | — | — | |
| SCHEMBL26050671 | 0.68 | KMT2A (0.44) | TSHRSMN1; SMN2 | |
| SCHEMBL28080959 | 0.68 | SSTR4 (0.40) | KDM4ESSTR4 | |
| SCHEMBL19732855 | 0.67 | KDM4E (0.47) | TAAR1KDM4ESSTR4MAPK1SMN1; SMN2 | |
| SCHEMBL11550393 | 0.64 | CYP1A2 (0.46) | KDM4ETSHRMAPK1 | |
| SCHEMBL1623962 | 0.64 | TAAR1 (0.60) | PRKCDPRKCHPRKCEPRKCQTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |