Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100117 | 0.89 | CHRM5 (0.48) | ACHECHRM5ADRA2CGNAI3GNAO1 | |
| SCHEMBL2673448 | 0.89 | CHRM5 (0.48) | ACHECHRM5ADRA2CGNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL2674762 | 0.87 | CHRM5 (0.46) | ACHECHRM5ADRA2CGNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL3539492 | 0.87 | CHRM5 (0.46) | ACHECHRM5ADRA2CGNAI3GNAO1 | |
| SCHEMBL1286687 | 0.84 | ACHE (0.78) | ACHECHRM5ADRA2CCARM1PRMT6 | |
| SCHEMBL16384768 | 0.81 | ACHE (0.61) | ACHECHRM5ADRA2CCARM1PRMT6 | |
| SCHEMBL12716490 | 0.80 | ACHE (0.65) | ACHECHRM5ADRA2CCARM1PRMT6 | |
| SCHEMBL12716944 | 0.80 | ACHE (0.65) | ACHECHRM5ADRA2CCARM1PRMT6 | |
| SCHEMBL12716498 | 0.80 | ACHE (0.65) | ACHECHRM5ADRA2CCARM1PRMT6 | |
| SCHEMBL12717053 | 0.80 | ACHE (0.65) | ACHECHRM5ADRA2CCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016518-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2023-02-16 | — | — | WO | disclosed |
| US-4163789-A | Anti-psychotic (cycloalkenylalkylpiperidino) benzamides | ANPHAR, S.A. (ES) | 1979-08-07 | — | — | US | disclosed |