Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 8/20 | 0.68 |
| ▸ | RAB9A | P51151 | 8/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.62 |
| ▸ | RELA | Q04206 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272502 | 0.86 | NPC1 (0.62) | EPHX2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11550130 | 0.85 | KDM4E (0.64) | EPHX2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL21933291 | 0.84 | EPHX2 (1.00) | EPHX2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1742667 | 0.81 | CYP1A2 (0.81) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL107421 | 0.81 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL179084 | 0.81 | NPC1 (0.79) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4647917 | 0.80 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL27666186 | 0.80 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL12875982 | 0.79 | RAB9A (0.75) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13923629 | 0.79 | NPC1 (0.81) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155915-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | disclosed |