Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 16/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548154 | 0.90 | ESR1 (0.56) | ESR1CNR1CNR2ESR2ENPP3 | |
| SCHEMBL11552334 | 0.87 | CNR1 (0.56) | ESR1CNR1CNR2ESR2TUBB4A | |
| SCHEMBL11548534 | 0.86 | ESR1 (0.57) | ESR1CNR1CNR2ESR2ENPP3 | |
| SCHEMBL11546507 | 0.84 | ESR1 (0.58) | ESR1CNR1CNR2ESR2 | |
| SCHEMBL11549732 | 0.84 | CNR2 (0.69) | ESR1CNR1CNR2ESR2TUBB4A | |
| SCHEMBL11547293 | 0.83 | ESR1 (0.60) | ESR1CNR1CNR2ESR2ENPP3 | |
| SCHEMBL11546770 | 0.81 | CNR1 (0.55) | ESR1CNR1CNR2ESR2TUBB4A | |
| SCHEMBL11550376 | 0.81 | ESR1 (0.52) | ESR1CNR1CNR2ESR2TUBB4A | |
| SCHEMBL6980679 | 0.80 | ESR1 (0.71) | ESR1CNR1CNR2ESR2TUBB4A | |
| SCHEMBL11546641 | 0.79 | TUBB4A (0.69) | ESR1CNR1CNR2ESR2TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133814-A | ANTITUMOR AGENTS | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |