⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500324 | 1.00 | — | — | |
| SCHEMBL11547948 | 1.00 | — | — | |
| SCHEMBL500323 | 1.00 | — | — | |
| SCHEMBL5868542 | 0.83 | — | — | |
| SCHEMBL5868544 | 0.83 | — | — | |
| SCHEMBL5868512 | 0.79 | — | — | |
| SCHEMBL10490587 | 0.77 | TSHR (0.35) | — | |
| SCHEMBL1192062 | 0.77 | — | — | |
| SCHEMBL9150748 | 0.76 | — | — | |
| SCHEMBL11601866 | 0.75 | LMNA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045475-A | Optically active alcohols and lower esters thereof | HOFFMANN-LA ROCHE INC. (US) | 1977-08-30 | — | — | US | claimed |
| WO-2025096734-A1 | MICROCAPSULES | FMC CORPORATION (US) | 2025-05-08 | — | — | WO | disclosed |
| US-20160375071-A1 | COMPOSITIONS AND METHODS COMPRISING YEAST ORGANISMS AND LIPID EXTRACTS THEREOF | R.F. TECHNOLOGY CONSULTANTS, INC. | 2016-12-29 | — | — | US | disclosed |
| US-4160865-A | Asymmetric synthesis | HOFFMANN-LA ROCHE INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4151360-A | Optically active amine salts | HOFFMANN-LA ROCHE INC. (US) | 1979-04-24 | — | — | US | disclosed |
| US-4110346-A | Tetramethyl chromanyl pentane derivatives | HOFFMANN-LA ROCHE INC. (US) | 1978-08-29 | — | — | US | disclosed |
| US-4102909-A | Optically active esters and amides | HOFFMANN-LA ROCHE INC. (US) | 1978-07-25 | — | — | US | disclosed |
| US-4094892-A | CLAISEN REARRANGEMENT | HOFFMANN-LA ROCHE INC. (US) | 1978-06-13 | — | — | US | disclosed |
| US-4088662-A | Optically active amides and process for producing the same | HOFFMANN-LA ROCHE INC. (US) | 1978-05-09 | — | — | US | disclosed |
| US-4086249-A | Tetramethyl chromanyl pentane amide | HOFFMANN-LA ROCHE INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4076739-A | Synthesis of vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4045475-A | Optically active alcohols and lower esters thereof | HOFFMANN-LA ROCHE INC. (US) | 1977-08-30 | — | — | US | disclosed |
| US-4016178-A | Synthesis of vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1977-04-05 | — | — | US | disclosed |
| US-4000169-A | ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 1976-12-28 | — | — | US | disclosed |