Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16671797 | 0.91 | KDM4E (0.59) | NPC1RAB9AKDM4EHPGDTSHR | |
| Hydrochloric Acid SCHEMBL5550609 | 0.90 | KDM4E (0.58) | NPC1RAB9AKDM4EHPGDTSHR | |
| SCHEMBL11546884 | 0.87 | MAPK13 (0.55) | NPC1RAB9AKDM4EHPGDTSHR | |
| SCHEMBL7865528 | 0.85 | KDM4E (0.69) | NPC1RAB9AKDM4EHPGDTSHR | |
| Hydrochloric Acid SCHEMBL11845983 | 0.84 | KDM4E (0.67) | NPC1RAB9AKDM4EHPGDTSHR | |
| SCHEMBL11547430 | 0.81 | PTGS2 (0.46) | NPC1RAB9AKDM4ETSHRPTGS2 | |
| SCHEMBL11545546 | 0.79 | NR3C2 (0.50) | NPC1RAB9AKDM4EHPGDTSHR | |
| SCHEMBL11546936 | 0.79 | NPC1 (0.48) | NPC1RAB9AKDM4EHPGDTSHR | |
| SCHEMBL2112872 | 0.79 | KDM4E (0.63) | NPC1RAB9AKDM4EHPGDTSHR | |
| SCHEMBL11379558 | 0.78 | TDP1 (0.46) | NPC1RAB9AHPGDTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163015-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4138405-A | BACTERICIDES | STERLING DRUG INC. (US) | 1979-02-06 | — | — | US | disclosed |