Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425406 | 0.83 | POLB (0.47) | HPGDALDH1A1CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL7353467 | 0.82 | HPGD (0.60) | HPGDALDH1A1CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL4994046 | 0.80 | SMN1; SMN2 (0.48) | HPGDALDH1A1CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL4994054 | 0.80 | POLB (0.43) | HPGDALDH1A1CYP2C19POLBESR2 | |
| SCHEMBL22733890 | 0.78 | HPGD (0.51) | HPGDALDH1A1CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL3223780 | 0.77 | HPGD (0.55) | HPGDALDH1A1CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL5045391 | 0.76 | HPGD (0.53) | HPGDALDH1A1CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL27847201 | 0.76 | HPGD (0.53) | HPGDALDH1A1CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL4775992 | 0.76 | HPGD (0.53) | HPGDALDH1A1CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL28062332 | 0.76 | HPGD (0.53) | HPGDALDH1A1CYP2C19POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143051-A | GREATER TISSUE SPECIFICITY OF ACTION | PFIZER INC. (US) | 1979-03-06 | — | — | US | disclosed |
| US-4113723-A | TISSUE SPECIFICITY | PFIZER INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-4102894-A | TISSUE SPECIFICITY | PFIZER INC. (US) | 1978-07-25 | — | — | US | disclosed |
| US-4080368-A | PROSTAGLANDINS | PFIZER INC. (US) | 1978-03-21 | — | — | US | disclosed |
| US-3980642-A | 15-Substitute D-ω-pentanorprostaglandins | PFIZER INC. (US) | 1976-09-14 | — | — | US | disclosed |
| US-3956284-A | INCREASED TISSUE SPECIFITY OF ACTION | PFIZER INC. (US) | 1976-05-11 | — | — | US | disclosed |