Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353467 | 0.87 | HPGD (0.60) | HPGDALDH1A1CYP2C19RAB9APOLB | |
| SCHEMBL28879909 | 0.86 | TAAR1 (0.53) | HPGDALDH1A1CYP2C19RAB9AUSP2 | |
| SCHEMBL3223780 | 0.86 | HPGD (0.55) | HPGDALDH1A1CYP2C19RAB9APOLB | |
| SCHEMBL15178187 | 0.85 | HPGD (0.50) | HPGDALDH1A1CYP2C19RAB9AUSP2 | |
| SCHEMBL7607464 | 0.85 | HPGD (0.50) | HPGDALDH1A1CYP2C19RAB9AUSP2 | |
| SCHEMBL27593897 | 0.82 | ALDH1A1 (0.52) | HPGDALDH1A1CYP2C19RAB9AUSP2 | |
| SCHEMBL27482820 | 0.80 | HPGD (0.56) | HPGDALDH1A1CYP2C19RAB9APOLB | |
| SCHEMBL5045391 | 0.80 | HPGD (0.53) | HPGDALDH1A1CYP2C19RAB9APOLB | |
| SCHEMBL4775992 | 0.80 | HPGD (0.53) | HPGDALDH1A1CYP2C19RAB9APOLB | |
| Ethylene Glycol SCHEMBL11811178 | 0.80 | CYP2C19 (0.53) | HPGDALDH1A1CYP2C19RAB9AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432268-A | Method for synthesizing cefalotin sodium drug intermediate 7-(2-thiophene acetamino) cefoperazone sodium | 厦门莱恩斯特信息科技有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-105541869-A | Method for synthesizing drug intermediate, i.e., 7-(2-thiophenacetyl amino)cephalosporin sodium, of cephalothin sodium | CHENGDU DONGDIAN AIER SCIENCE AND TECH CO LTD | 2016-05-04 | — | — | CN | disclosed |