SCHEMBL11549245

SCHEMBL11549245

O=C1NC(C(O)c2ccccc2)CO1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.39
GBA1 P04062 1/20 0.37
HSD17B2 P37059 1/20 0.36
LMNA P02545 2/20 0.33
MAPK1 P28482 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB3 P13945 1/20 0.33
KCNH2 Q12809 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NR3C1 P04150 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8882442 1.00 EPHX1 (0.39) EPHX1GBA1HSD17B2LMNAMAPK1
SCHEMBL8882439 1.00 EPHX1 (0.39) EPHX1GBA1HSD17B2LMNAMAPK1
SCHEMBL11547120 0.84 HSD17B2 (0.36) HSD17B2KCNH2SLC6A2SLC6A4SLC6A3
SCHEMBL5168082 0.83 DAO (0.37)
SCHEMBL5168090 0.83 DAO (0.37)
SCHEMBL5182311 0.83 DAO (0.37)
SCHEMBL8882036 0.83 ALDH1A1 (0.33) LMNAMAPK1SLC6A4
SCHEMBL12733121 0.80 ALDH1A1 (0.35)
SCHEMBL6667996 0.78 EPHX1 (0.37) EPHX1GBA1HSD17B2LMNAMAPK1
SCHEMBL6668003 0.78 EPHX1 (0.37) EPHX1GBA1HSD17B2LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4179442-A 4-(Alpha-hydroxy-isopropyl)-5-phenyl-oxazolidin-2-one HARTLEBEN YORK (DE) 1979-12-18 US disclosed
US-4139538-A ANTIEPILEPTIC, ANTICONVULSANT, TRANQUILIZERS, SEDATIVES NORDMARK-WERKE GMBH (DE) 1979-02-13 US disclosed