SCHEMBL11549264

SCHEMBL11549264

Cc1cc(Cl)ccc1N=CN(C)[S]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.51
ADRA2A P08913 1/20 0.51
ALDH1A1 P00352 4/20 0.42
HPGD P15428 2/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KDM4E B2RXH2 2/20 0.40
MAPT P10636 1/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
NOX1 Q9Y5S8 1/20 0.38
HTT P42858 1/20 0.37
GAA P10253 2/20 0.36
POLB P06746 1/20 0.34
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11549260 1.00 CYP3A4 (0.51) CYP3A4ADRA2AALDH1A1HPGDTSHR
Chlordimeform SCHEMBL8380830 0.87 CYP3A4 (0.53) CYP3A4ADRA2AALDH1A1HPGDTSHR
Chlordimeform SCHEMBL22934 0.87 CYP3A4 (0.53) CYP3A4ADRA2AALDH1A1HPGDTSHR
Chlordimeform SCHEMBL29356157 0.87 CYP3A4 (0.53) CYP3A4ADRA2AALDH1A1HPGDTSHR
Chlordimeform SCHEMBL5510656 0.87 CYP3A4 (0.53) CYP3A4ADRA2AALDH1A1HPGDTSHR
Chlordimeform SCHEMBL74460 0.87 CYP3A4 (0.53) CYP3A4ADRA2AALDH1A1HPGDTSHR
Chlordimeform SCHEMBL160021 0.86 CYP3A4 (0.51) CYP3A4ADRA2AALDH1A1HPGDTSHR
Chlordimeform SCHEMBL160020 0.86 CYP3A4 (0.51) CYP3A4ADRA2AALDH1A1HPGDTSHR
Chlordimeform SCHEMBL7185165 0.86 CYP3A4 (0.51) CYP3A4ADRA2AALDH1A1HPGDTSHR
SCHEMBL11549269 0.84 CYP3A4 (0.50) CYP3A4ADRA2AALDH1A1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4152454-A Insecticidal compositions comprising N'-aryl-N-methylformamidines and 3-phenoxybenzyl carboxylates FMC CORPORATION (US) 1979-05-01 US disclosed