Chlordimeform

Chlordimeform

SCHEMBL8380830

Cc1cc(Cl)ccc1N=CN(C)C.Cc1cc(Cl)ccc1N=CN(C)C

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.53
ADRA2A P08913 1/20 0.53
KMT2A Q03164 2/20 0.44
ALDH1A1 P00352 8/20 0.43
HPGD P15428 4/20 0.43
HSD17B10 Q99714 3/20 0.43
TSHR P16473 2/20 0.43
KDM4E B2RXH2 6/20 0.41
MAPT P10636 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
SMN1; SMN2 Q16637 6/20 0.39
RAB9A P51151 4/20 0.39
NPC1 O15118 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlordimeform SCHEMBL5510656 1.00 CYP3A4 (0.53) CYP3A4ADRA2AKMT2AALDH1A1HPGD
Chlordimeform SCHEMBL29356157 1.00 CYP3A4 (0.53) CYP3A4ADRA2AKMT2AALDH1A1HPGD
Chlordimeform SCHEMBL22934 1.00 CYP3A4 (0.53) CYP3A4ADRA2AKMT2AALDH1A1HPGD
Chlordimeform SCHEMBL74460 1.00 CYP3A4 (0.53) CYP3A4ADRA2AKMT2AALDH1A1HPGD
Chlordimeform SCHEMBL160020 0.98 CYP3A4 (0.51) CYP3A4ADRA2AKMT2AALDH1A1HPGD
Chlordimeform SCHEMBL7185165 0.98 CYP3A4 (0.51) CYP3A4ADRA2AKMT2AALDH1A1HPGD
Chlordimeform SCHEMBL160021 0.98 CYP3A4 (0.51) CYP3A4ADRA2AKMT2AALDH1A1HPGD
Amitraz SCHEMBL2044810 0.89 CYP3A4 (0.73) CYP3A4ADRA2AKMT2AALDH1A1HPGD
SCHEMBL11549264 0.87 CYP3A4 (0.51) CYP3A4ADRA2AALDH1A1HPGDHSD17B10
SCHEMBL11549260 0.87 CYP3A4 (0.51) CYP3A4ADRA2AALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
US-5925676-A INSECICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-20 US disclosed
US-5922880-A CONTROLLING INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-13 US disclosed
US-5883262-A INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-16 US disclosed
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
US-5817880-A 2-FLUOROALKYL-4-HYDROXYCYCLOPENT-2-ENONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-06 US disclosed
US-5756522-A INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-05-26 US disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5684022-A ANTIFERTILITY AGENT PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-11-04 US disclosed
US-5672779-A INTERMEDIATE FOR PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-09-30 US disclosed