Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.63 |
| ▸ | MAOA | P21397 | 8/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549468 | 1.00 | MAOB (0.63) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL29952282 | 0.76 | PTPN1 (1.00) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL127924 | 0.76 | PTPN1 (1.00) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL31227087 | 0.75 | MAOB (0.68) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL11307220 | 0.75 | MAOB (0.68) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL1305130 | 0.75 | MAOB (0.71) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL1102245 | 0.75 | MAOB (0.71) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL28874629 | 0.75 | MAOB (0.71) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL29366939 | 0.71 | MAOB (0.51) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL2525949 | 0.71 | MAOB (0.51) | MAOBMAOAPTPN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151180-A | INTERMEDIATES FOR ANTIALLERGENS, ANTIHISTAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-04-24 | — | — | US | disclosed |