Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 1.00 |
| ▸ | MAOB | P27338 | 6/20 | 1.00 |
| ▸ | MAOA | P21397 | 5/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127924 | 1.00 | PTPN1 (1.00) | PTPN1MAOBMAOAPTPN2POLB | |
| Thiosemicarbazide SCHEMBL28340570 | 0.86 | PTPN1 (0.74) | PTPN1MAOBMAOAPTPN2POLB | |
| SCHEMBL7025708 | 0.86 | PTPN1 (0.86) | PTPN1MAOBMAOAPTPN2POLB | |
| SCHEMBL30842883 | 0.86 | PTPN1 (0.75) | PTPN1MAOBMAOAPTPN2POLB | |
| SCHEMBL96940 | 0.86 | PTPN1 (0.75) | PTPN1MAOBMAOAPTPN2POLB | |
| SCHEMBL1102245 | 0.83 | MAOB (0.71) | PTPN1MAOBMAOAPTGS2MEN1 | |
| SCHEMBL28874629 | 0.83 | MAOB (0.71) | PTPN1MAOBMAOAPTGS2ALDH1A1 | |
| SCHEMBL1305130 | 0.83 | MAOB (0.71) | PTPN1MAOBMAOAPTGS2KMT2A | |
| SCHEMBL28132715 | 0.82 | MAOB (0.70) | PTPN1MAOBMAOAPTPN2POLB | |
| SCHEMBL9618067 | 0.79 | PTPN1 (0.66) | PTPN1MAOBMAOAPTPN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |