Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 5/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PNLIP | P16233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067066 | 0.89 | KCNH2 (0.41) | PLK1KCNH2ABL1EGFRSYK | |
| SCHEMBL11348780 | 0.81 | PLK1 (0.47) | PLK1ABL1S1PR3EGFRSYK | |
| SCHEMBL11545186 | 0.81 | PLK1 (0.44) | PLK1ABL1S1PR3EGFRSYK | |
| SCHEMBL11313119 | 0.80 | PLK1 (0.45) | PLK1ABL1PNLIP | |
| SCHEMBL11309283 | 0.79 | PLK1 (0.58) | PLK1ABL1EGFRSYKALOX5 | |
| SCHEMBL11320812 | 0.79 | PLK1 (0.58) | PLK1ABL1EGFRSYKALOX5 | |
| SCHEMBL11307858 | 0.79 | PLK1 (0.58) | PLK1ABL1EGFRSYKALOX5 | |
| SCHEMBL11307705 | 0.79 | PLK1 (0.58) | PLK1ABL1EGFRSYKALOX5 | |
| SCHEMBL5025350 | 0.79 | PLK1 (0.49) | PLK1KCNH2S1PR3ALOX5PTGS2 | |
| SCHEMBL11318599 | 0.79 | PLK1 (0.58) | PLK1ABL1EGFRSYKALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146546-A | LOWER SERUM STEROLS AND TRIGLYCERIDES | AMERICAN CYANAMID COMPANY (US) | 1979-03-27 | — | — | US | disclosed |
| US-4058550-A | HYPOLIPEMIC | AMERICAN CYANAMID COMPANY (US) | 1977-11-15 | — | — | US | disclosed |