Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.80 |
| ▸ | HPGD | P15428 | 5/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.80 |
| ▸ | POLB | P06746 | 3/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.80 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.80 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.80 |
| ▸ | CLK2 | P49760 | 1/20 | 0.80 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | TOP2A | P11388 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL29163210 | 0.99 | KDM4E (0.79) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| SCHEMBL27918942 | 0.99 | KDM4E (0.79) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| SCHEMBL28079403 | 0.99 | KDM4E (0.79) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| Water SCHEMBL28828205 | 0.99 | KDM4E (0.79) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| Hydrochloric Acid SCHEMBL9751979 | 0.99 | KDM4E (0.79) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| Water SCHEMBL27625917 | 0.99 | KDM4E (0.79) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| Acetic Acid SCHEMBL28525396 | 0.98 | KDM4E (0.77) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| SCHEMBL9773833 | 0.96 | KDM4E (0.75) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| SCHEMBL27002955 | 0.95 | KDM4E (0.74) | KDM4EALDH1A1HPGDKCNH2HSD17B10 | |
| SCHEMBL11975675 | 0.95 | KDM4E (0.81) | KDM4EALDH1A1HPGDKCNH2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102198138-B | Compound antitubercular preparation containing gatifloxacin, and preparation method thereof | UNIV SHENYANG PHARMACEUTICAL | 2014-05-21 | — | — | CN | claimed |
| CN-100496469-C | Gatifloxacin capsules and method of preparing the same | SHANDONG LUOXIN PHARMACEUTICAL (CN) | 2009-06-10 | — | — | CN | claimed |
| CN-101254179-A | Gatifloxacin capsules and method of preparing the same | SHANDONG LUOXIN PHARMACEUTICAL (CN) | 2008-09-03 | — | — | CN | claimed |
| US-4980470-A | 8-alkoxyquinolonecarboxylic acid and salts thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-12-25 | — | — | US | claimed |
| EP-0241206-A2 | Quinoline-3-carboxylic acid derivatives, their preparation and use | Sankyo Company Limited (JP) | 1987-10-14 | — | — | EP | claimed |
| JP-6080640-A | — | — | None | — | — | JP | disclosed |
| JP-6092937-A | — | — | None | — | — | JP | disclosed |
| JP-62252772-A | — | — | None | — | — | JP | disclosed |
| US-10087165-B2 | Fluoroquinolones and use thereof to treat bacterial infections | SORBONNE UNIVERSITE (FR) | 2018-10-02 | — | — | US | disclosed |
| US-20170144992-A1 | NOVEL FLUOROQUINOLONES AND USE THEREOF TO TREAT BACTERIAL INFECTIONS | UNIVERSITÉ PIERRE ET MARIE CURIE - PARIS 6 (UPMC) (FR) | 2017-05-25 | — | — | US | disclosed |
| US-20170144992-A1 | NOVEL FLUOROQUINOLONES AND USE THEREOF TO TREAT BACTERIAL INFECTIONS | UNIVERSITÉ PIERRE ET MARIE CURIE - PARIS 6 (UPMC) (FR) | 2017-05-25 | — | — | US | disclosed |
| US-20170144992-A1 | NOVEL FLUOROQUINOLONES AND USE THEREOF TO TREAT BACTERIAL INFECTIONS | UNIVERSITÉ PIERRE ET MARIE CURIE - PARIS 6 (UPMC) (FR) | 2017-05-25 | — | — | US | disclosed |
| JP-H0680640-A | 8-ALKOXYQUINOLONECARBOXYLIC ACID HAVING EXCELLENT SELECTIVE TOXICITY, ITS SALT AND ITS PRODUCTION | KYORIN PHARMACEUT CO LTD | 1994-03-22 | — | — | JP | disclosed |
| US-5043450-A | Bactericides | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| US-4997943-A | Bactericides | SANKYO COMPANY LIMITED (JP) | 1991-03-05 | — | — | US | disclosed |
| US-4980470-A | 8-alkoxyquinolonecarboxylic acid and salts thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-12-25 | — | — | US | disclosed |
| JP-S62252772-A | 8-ALKOXYQUINOLONECARBOXYLIC ACID HAVING EXCELLENT SELECTIVE TOXICITY, ITS SALT AND PRODUCTION THEREOF | KYORIN PHARMACEUT CO LTD | 1987-11-04 | — | — | JP | disclosed |
| EP-0241206-A2 | Quinoline-3-carboxylic acid derivatives, their preparation and use | Sankyo Company Limited (JP) | 1987-10-14 | — | — | EP | disclosed |
| EP-0230295-A2 | 8-alkoxyquinolonecarboxylic acid and salts thereof excellent in the selective toxicity and process of preparing the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-07-29 | — | — | EP | disclosed |
| JP-H00692937-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10087165-B2 | Fluoroquinolones and use thereof to treat bacterial infections | CFTR, NQO2, FPR1 | KDM4E 3086/4885ALDH1A1 4095/4885HPGD 755/4885 |
| US-20170144992-A1 | NOVEL FLUOROQUINOLONES AND USE THEREOF TO TREAT BACTERIAL INFECTIONS | CFTR, IRF3, FPR1 | KDM4E 3242/4885ALDH1A1 4490/4885HPGD 1216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.