Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | EEF2K | O00418 | 2/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549842 | 0.87 | MC4R (0.33) | MC4RKMT2ACXCL8SMN1; SMN2 | |
| SCHEMBL11553311 | 0.86 | GLS (0.38) | KMT2AALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11548090 | 0.86 | CYP2C9 (0.35) | MC4RALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11558084 | 0.85 | AOC3 (0.38) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11493875 | 0.84 | MC4R (0.43) | MC4RMEN1KMT2AALDH1A1CXCL8 | |
| SCHEMBL11553042 | 0.80 | CYP2C19 (0.38) | MEN1KMT2A | |
| SCHEMBL11550218 | 0.78 | KMT2A (0.35) | KMT2AALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11549622 | 0.76 | KCNA5 (0.36) | ALDH1A1 | |
| SCHEMBL11486373 | 0.75 | MC4R (0.34) | MC4RKMT2AALDH1A1CXCL8LMNA | |
| SCHEMBL11485460 | 0.72 | CYP2C19 (0.36) | MC4RALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172204-A | Method for preparing 4,5-dihydro-2-alkoxycarbonylamino-5-carbocyclic aryl imidazoles and intermediates thereof | SYNTEX (U.S.A.) INC. (US) | 1979-10-23 | — | — | US | disclosed |
| EP-0001500-A1 | 1-Carbocyclic aryl-2-mono or -bis(alkoxycarbonyl) guanidino ethanes, and methods for their preparation and the preparation therefrom of 4,5-dihydro-2-alkoxycarbonylamino-5-carbocyclic aryl imidazoles | SYNTEX (U.S.A.) INC. (US) | 1979-04-18 | — | — | EP | disclosed |