Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24806572 | 0.92 | GAA (0.60) | GAANPSR1KDM4EHSD17B10HPGD | |
| SCHEMBL17479424 | 0.92 | NPSR1 (0.60) | GAANPSR1KDM4EHSD17B10HPGD | |
| SCHEMBL14116961 | 0.92 | GAA (0.60) | GAANPSR1KDM4EHSD17B10HPGD | |
| SCHEMBL14402167 | 0.91 | GAA (0.68) | GAANPSR1KDM4EHSD17B10HPGD | |
| SCHEMBL11815554 | 0.90 | GAA (0.72) | GAANPSR1KDM4EHSD17B10HPGD | |
| SCHEMBL4373468 | 0.90 | MAPT (0.59) | GAANPSR1KDM4EHSD17B10HPGD | |
| SCHEMBL11175140 | 0.89 | NPSR1 (0.57) | GAANPSR1KDM4EHSD17B10HPGD | |
| SCHEMBL9267668 | 0.89 | GAA (0.70) | GAANPSR1KDM4EHSD17B10HPGD | |
| SCHEMBL1107148 | 0.89 | GAA (0.70) | GAANPSR1KDM4EHSD17B10HPGD | |
| SCHEMBL23605965 | 0.87 | GAA (0.56) | GAANPSR1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148915-A | ARTERIOSCLEROSIS AND HYPERLIPEMIA TREATMENT DIURETICS, ANTICHOLESTEROL AND ANTILIPEMIC | ALBERT ROLLAND, S.A. (FR) | 1979-04-10 | — | — | US | disclosed |