Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707685 | 0.95 | GAA (0.64) | MAPTHPGDGAANPSR1L3MBTL1 | |
| SCHEMBL11550281 | 0.90 | GAA (0.70) | MAPTHPGDRAB9AGAANPSR1 | |
| SCHEMBL4373011 | 0.88 | HPGD (0.49) | MAPTHPGDRAB9AGAANPSR1 | |
| SCHEMBL16035326 | 0.83 | NPSR1 (0.66) | MAPTHPGDGAANPSR1L3MBTL1 | |
| SCHEMBL24243599 | 0.83 | MAPT (0.73) | MAPTHPGDRAB9AGAANPSR1 | |
| SCHEMBL4373786 | 0.83 | GAA (0.51) | MAPTHPGDGAANPSR1LMNA | |
| SCHEMBL4373788 | 0.83 | GAA (0.51) | MAPTHPGDGAANPSR1LMNA | |
| SCHEMBL17479424 | 0.83 | NPSR1 (0.60) | MAPTHPGDGAANPSR1POLB | |
| SCHEMBL14116961 | 0.83 | GAA (0.60) | MAPTHPGDGAANPSR1LMNA | |
| SCHEMBL24806572 | 0.83 | GAA (0.60) | MAPTHPGDGAANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118747-A1 | NOVEL HYDROXY FUNCTIONALIZED 1, 2, 4-TRIOXANES AS ANTIMALARIAL AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-10-01 | — | — | WO | disclosed |