SCHEMBL11550359

SCHEMBL11550359

CCc1ccc(OC(=O)c2ccc(-c3ccc(CC)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.59
MAPT P10636 5/20 0.53
THRB P10828 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
ALDH1A1 P00352 2/20 0.52
RXRA P19793 2/20 0.51
RXRB P28702 2/20 0.51
KMT2A Q03164 2/20 0.49
F2 P00734 1/20 0.49
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
RAB9A P51151 1/20 0.49
HSD17B10 Q99714 2/20 0.49
PARP10 Q53GL7 1/20 0.47
PLK1 P53350 1/20 0.47
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
HSP90AA1 P07900 1/20 0.47
RECQL P46063 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12154284 1.00 TP53 (0.59) TP53MAPTTHRBSMN1; SMN2ALDH1A1
SCHEMBL26832413 1.00 TP53 (0.59) TP53MAPTTHRBSMN1; SMN2ALDH1A1
SCHEMBL12154217 0.94 ALDH1A1 (0.57) TP53MAPTTHRBSMN1; SMN2ALDH1A1
SCHEMBL12199916 0.94 ALDH1A1 (0.57) TP53MAPTTHRBSMN1; SMN2ALDH1A1
SCHEMBL26832415 0.94 ALDH1A1 (0.57) TP53MAPTTHRBSMN1; SMN2ALDH1A1
SCHEMBL12154283 0.94 ALDH1A1 (0.57) TP53MAPTTHRBSMN1; SMN2ALDH1A1
SCHEMBL24581822 0.93 SMN1; SMN2 (0.57) TP53MAPTTHRBSMN1; SMN2ALDH1A1
SCHEMBL11550715 0.93 TP53 (0.54) TP53MAPTTHRBSMN1; SMN2ALDH1A1
SCHEMBL14539496 0.93 TP53 (0.54) TP53MAPTTHRBSMN1; SMN2ALDH1A1
SCHEMBL10000964 0.93 TP53 (0.54) TP53MAPTTHRBSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-20230131540-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT AND COMPOUND DIC CORPORATION (JP) 2023-04-27 US disclosed
US-4136053-A BIPHENYL ESTERS AND LIQUID CRYSTALLINE MIXTURES COMPRISING THEM MERCK PATENT GESELLSCHAFT MIT BESCHANKTER HAFTUNG (DE) 1979-01-23 US disclosed
US-4065489-A Biphenyl esters and liquid crystalline mixtures comprising them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 TP53 2799/4885MAPT 1064/4885THRB 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.