Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.54 |
| ▸ | CMA1 | P23946 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11806643 | 0.81 | MEN1 (0.48) | AHRCMA1MEN1KMT2AMAPT | |
| SCHEMBL11813352 | 0.81 | MEN1 (0.55) | AHRCMA1MEN1KMT2AMAPT | |
| SCHEMBL11800662 | 0.81 | KMT2A (0.50) | AHRCMA1MEN1KMT2AMAPT | |
| SCHEMBL11812432 | 0.81 | MEN1 (0.50) | AHRCMA1MEN1KMT2AMAPT | |
| SCHEMBL11806756 | 0.79 | MEN1 (0.46) | AHRCMA1MEN1KMT2AMAPT | |
| SCHEMBL11553211 | 0.79 | PDE3B (0.52) | MEN1KMT2AMAPTLMNACCNB2 | |
| SCHEMBL11483378 | 0.79 | KMT2A (0.76) | AHRCMA1MEN1KMT2AMAPT | |
| SCHEMBL11806665 | 0.79 | MEN1 (0.48) | AHRCMA1MEN1KMT2AMAPT | |
| SCHEMBL11810776 | 0.78 | NR1H2 (0.45) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL11804090 | 0.78 | CASP3 (0.49) | MAPTGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984398-A | 1,5-Benzodiazepine-2,4-diones | ROUSSEL-UCLAF (FR) | 1976-10-05 | — | — | US | claimed |
| US-4138572-A | Malonanilic derivatives | ROUSSEL UCLAF (FR) | 1979-02-06 | — | — | US | disclosed |
| US-4001408-A | SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESSES AND COMPOSITION INCLUDING THOSE | ROUSSEL-UCLAF (FR) | 1977-01-04 | — | — | US | disclosed |
| US-3984398-A | 1,5-Benzodiazepine-2,4-diones | ROUSSEL-UCLAF (FR) | 1976-10-05 | — | — | US | disclosed |
| US-RE28972-E | SEDATIVES, ANTICONVULSANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-09-21 | — | — | US | disclosed |