SCHEMBL11550449

SCHEMBL11550449

Cc1ccc(C(=O)c2ccccc2C(=O)O)cc1Cl

nearest known ligand 0.73

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.73
POLB P06746 2/20 0.68
CDC25B P30305 3/20 0.62
CDC25A P30304 1/20 0.62
HSD17B10 Q99714 1/20 0.62
AKR1C3 P42330 3/20 0.60
NR4A1 P22736 1/20 0.60
ATM Q13315 1/20 0.53
LMNA P02545 1/20 0.51
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
KMT2A Q03164 1/20 0.49
KDM4E B2RXH2 2/20 0.47
GLA P06280 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15100602 0.87 ALDH1A1 (0.54) ALDH1A1POLBLMNAKMT2AKDM4E
SCHEMBL1786654 0.85 ALDH1A1 (1.00) ALDH1A1POLBCDC25BCDC25AHSD17B10
SCHEMBL31333081 0.85 ALDH1A1 (1.00) ALDH1A1POLBCDC25BCDC25AHSD17B10
SCHEMBL31364358 0.85 ALDH1A1 (0.73) ALDH1A1POLBCDC25BCDC25AHSD17B10
SCHEMBL1443365 0.85 ALDH1A1 (0.73) ALDH1A1POLBCDC25BCDC25AHSD17B10
SCHEMBL13176761 0.83 ATM (0.55) ALDH1A1POLBATMLMNAKMT2A
SCHEMBL257371 0.83 KMT2A (0.51) ALDH1A1POLBHSD17B10LMNACYP3A4
SCHEMBL2924706 0.80 HPGD (0.54) ALDH1A1POLBLMNACYP3A4KMT2A
SCHEMBL15100859 0.80 KMT2A (0.54) ALDH1A1POLBLMNAKMT2AKDM4E
SCHEMBL8864729 0.80 ALDH1A1 (0.66) ALDH1A1POLBCDC25BCDC25AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4163810-A Ultraviolet curable powder paints SCM CORPORATION (US) 1979-08-07 US disclosed
US-4129488-A Ultraviolet curable epoxy-polyester powder paints SCM CORPORATION (US) 1978-12-12 US disclosed
US-4105518-A POLYMER CONTAINING ACRYLYL, ACRYLAMIDE OR ALLYL UNSATURATED GROUPS, REACTED WITH SECONDARY AMINE AND NEUTRALIZED, SENSITIZER SCM CORPORATION (US) 1978-08-08 US disclosed
US-4052280-A PHOTOSENTIZER IN BACKBONE OF POLYMER SCM CORPORATION (US) 1977-10-04 US disclosed
US-4040925-A PAINTS; CHEMICALLY BONDED ULTRAVIOLET SENSITIZER SCM CORPORATION (US) 1977-08-09 US disclosed
US-4039414-A ACRYLYL, ACRYLAMIDE, OR ALLYL POLYMERS, BENZALDEHYDE SENSITIZER SCM CORPORATION (US) 1977-08-02 US disclosed