Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2354562 | 0.87 | POLB (0.30) | POLBTSHRSLC1A2MEN1CYP1A2 | |
| SCHEMBL1199315 | 0.78 | CYP19A1 (0.30) | — | |
| SCHEMBL18105684 | 0.77 | APLNR (0.38) | POLBTSHRSLC1A2MEN1CYP1A2 | |
| SCHEMBL18105681 | 0.77 | APLNR (0.38) | POLBTSHRSLC1A2MEN1CYP1A2 | |
| SCHEMBL1199310 | 0.77 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL11665889 | 0.74 | FFAR3 (0.43) | POLBTSHRSLC1A2MEN1CYP1A2 | |
| SCHEMBL11551082 | 0.74 | POLB (0.33) | POLBTSHREPHX1SLC6A12SLC6A11 | |
| SCHEMBL2354559 | 0.72 | POLB (0.30) | POLBTSHRSLC1A2MEN1CYP1A2 | |
| SCHEMBL29861464 | 0.72 | NR1H4 (0.33) | — | |
| SCHEMBL301673 | 0.71 | EPHX1 (0.45) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157384-A | Compositions having a physiological cooling effect | WILKINSON SWORD LIMITED (GB) | 1979-06-05 | — | — | US | disclosed |