Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1150339 | 0.86 | KMT2A (0.46) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL1150338 | 0.85 | MEN1 (0.62) | MEN1KMT2AGAAALDH1A1GRIN2D | |
| SCHEMBL14742899 | 0.85 | MEN1 (0.62) | MEN1KMT2AGAAALDH1A1GRIN2D | |
| SCHEMBL14742898 | 0.85 | MEN1 (0.62) | MEN1KMT2AGAAALDH1A1GRIN2D | |
| SCHEMBL23628176 | 0.84 | MEN1 (0.43) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL29485576 | 0.84 | MEN1 (0.57) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL1237159 | 0.84 | MEN1 (0.57) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL1071345 | 0.83 | KMT2A (0.53) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL23627827 | 0.82 | MEN1 (0.42) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL11545749 | 0.79 | MEN1 (0.62) | MEN1KMT2APOLBGAAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4142036-A | Polyphenylcarboxylic acid adamantane compounds and polymers prepared therefrom | STANDARD OIL COMPANY (INDIANA) (US) | 1979-02-27 | — | — | US | disclosed |