SCHEMBL1237159

SCHEMBL1237159

Cc1cc(C23CC4CC(C2)CC(c2ccc(O)c(C)c2)(C4)C3)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
POLB P06746 1/20 0.57
GAA P10253 1/20 0.57
GFER P55789 1/20 0.57
ESR1 P03372 4/20 0.49
ESR2 Q92731 3/20 0.49
ALDH1A1 P00352 2/20 0.44
PGR P06401 3/20 0.41
LMNA P02545 1/20 0.41
SPHK2 Q9NRA0 1/20 0.40
SPHK1 Q9NYA1 1/20 0.40
HSD11B1 P28845 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29485576 1.00 MEN1 (0.57) MEN1KMT2APOLBGAAGFER
SCHEMBL6759186 0.90 ESR1 (0.51) MEN1KMT2APOLBGAAGFER
SCHEMBL14829735 0.90 MEN1 (0.71) MEN1KMT2APOLBGAAGFER
SCHEMBL11550837 0.84 MEN1 (0.44) MEN1KMT2APOLBGAAGFER
SCHEMBL1972365 0.84 MEN1 (0.79) MEN1KMT2APOLBGAAGFER
SCHEMBL17042474 0.83 ESR1 (0.45) MEN1KMT2APOLBGAAGFER
SCHEMBL4954586 0.82 MEN1 (0.46) MEN1KMT2APOLBGAAGFER
SCHEMBL3977955 0.81 MEN1 (0.59) MEN1KMT2APOLBGAAGFER
SCHEMBL4606562 0.81 MEN1 (0.41) MEN1KMT2APOLBGAAGFER
SCHEMBL2048427 0.81 ACHE (0.43) MEN1KMT2APOLBGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11269263-B2 Bischloroformate composition, bischloroformate composition production method, bischloroformate composition-containing solution, polycarbonate resin, polycarbonate resin production method, coating liquid, electrophotographic photoreceptor, and electrophotographic device IDEMITSU KOSAN CO., LTD. (JP) 2022-03-08 US disclosed
EP-3392235-B1 BISCHLOROFORMATE COMPOSITION, BISCHLOROFORMATE COMPOSITION PRODUCTION METHOD, BISCHLOROFORMATE COMPOSITION CONTAINING SOLUTION, POLYCARBONATE RESIN, POLYCARBONATE RESIN PRODUCTION METHOD, COATING LIQUID, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC DEVICE IDEMITSU KOSAN CO (JP) 2020-04-29 EP disclosed
US-20180364598-A1 BISCHLOROFORMATE COMPOSITION, BISCHLOROFORMATE COMPOSITION PRODUCTION METHOD, BISCHLOROFORMATE COMPOSITION-CONTAINING SOLUTION, POLYCARBONATE RESIN, POLYCARBONATE RESIN PRODUCTION METHOD, COATING LIQUID, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-12-20 US disclosed
EP-3392235-A1 BISCHLOROFORMATE COMPOSITION, BISCHLOROFORMATE COMPOSITION PRODUCTION METHOD, BISCHLOROFORMATE COMPOSITION CONTAINING SOLUTION, POLYCARBONATE RESIN, POLYCARBONATE RESIN PRODUCTION METHOD, COATING LIQUID, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC DEVICE Idemitsu Kosan Co., Ltd (JP) 2018-10-24 EP disclosed
CN-105906509-B Method for producing bischloroformate compound 出光兴产株式会社 2018-04-06 CN disclosed
EP-2687907-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2018-02-14 EP disclosed
EP-2447299-B1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO (JP) 2017-11-29 EP disclosed
EP-2799461-B1 POLYCARBONATE COPOLYMER, AND COATING LIQUID AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING SAME IDEMITSU KOSAN CO (JP) 2017-10-11 EP disclosed
EP-2746314-B1 POLYCARBONATE RESIN AND COATING SOLUTION CONTAINING SAME, AND MOLDED ARTICLE PRODUCED BY MOLDING SAID COATING SOLUTION IDEMITSU KOSAN CO (JP) 2017-07-05 EP disclosed
EP-2682415-B1 POLYCARBONATE COPOLYMER, COATING FLUID USING SAME, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND METHOD FOR PRODUCING POLYCARBONATE COPOLYMER IDEMITSU KOSAN CO (JP) 2017-02-01 EP disclosed
US-20080242896-A1 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2008-10-02 US disclosed
EP-1336597-B1 Hydroxyphenyl adamantanes and process for the production of the same HONSHU CHEMICAL IND (JP) 2008-07-16 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed
US-6720460-B2 FORMING HEAT RESISTANT, MECHANICAL STRENGTH POLYMER ADDITIVES; ACID CATALYZED REACTION OF ADAMANTANE DIOL OR TRIOL WITH PHENOLIC DERIVATIVE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2004-04-13 US disclosed
US-20030187307-A1 Hydroxyphenyl adamantanes and process for the production of the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2003-10-02 US disclosed
EP-1336597-A1 Hydroxyphenyl adamantanes and process for the production of the same Honshu Chemical Industry Co., Ltd. (JP) 2003-08-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180364598-A1 BISCHLOROFORMATE COMPOSITION, BISCHLOROFORMATE COMPOSITION PRODUCTION METHOD, BISCHLOROFORMATE COMPOSITION-CONTAINING SOLUTION, POLYCARBONATE RESIN, POLYCARBONATE RESIN PRODUCTION METHOD, COATING LIQUID, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC DEVICE NR2E3, REV1, PBRM1 MEN1 424/4885KMT2A 664/4885POLB 2512/4885
US-20030187307-A1 Hydroxyphenyl adamantanes and process for the production of the same CYP8B1, DHPS, P4HA1 MEN1 1025/4885KMT2A 4019/4885POLB 727/4885
US-11269263-B2 Bischloroformate composition, bischloroformate composition production method, bischloroformate composition-containing solution, polycarbonate resin, polycarbonate resin production method, coating liquid, electrophotographic photoreceptor, and electrophotographic device NR2E3, REV1, PBRM1 MEN1 424/4885KMT2A 664/4885POLB 2512/4885
US-20080242896-A1 1,3-Bis(3-Formyl-4-Hydroxyphenyl)Adamantanes and Polynuclear Polyphenols Derived Therefrom HNMT, NEFM, CD69 MEN1 4682/4885KMT2A 2847/4885POLB 457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.