Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9590123 | 0.82 | PPARA (0.52) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL135713 | 0.82 | PPARA (0.72) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL3158911 | 0.82 | PPARA (0.67) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL29184208 | 0.82 | PPARA (0.52) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL11734716 | 0.81 | PPARA (0.50) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL3573347 | 0.81 | PPARA (0.50) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL4688589 | 0.81 | PPARA (0.48) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL1805865 | 0.80 | PPARA (0.53) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL21991451 | 0.79 | PPARA (0.46) | PPARACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL15545847 | 0.79 | CNR1 (0.46) | PPARACYP1A2CYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176193-A | ANTILIPEMIC, ANTICHLOESTEROL AGENTS | SOCIETE D'ETUDES DE PRODUITS CHIMIQUES (FR) | 1979-11-27 | — | — | US | disclosed |
| US-4151303-A | Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions | BOEHRINGER MANNHEIM GMBH (DE) | 1979-04-24 | — | — | US | disclosed |