Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | PPARG | P37231 | 4/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.62 |
| ▸ | FABP2 | P12104 | 2/20 | 0.62 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537290 | 0.94 | PPARA (0.66) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL822492 | 0.91 | PPARA (0.77) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11539959 | 0.90 | PPARA (0.60) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11458283 | 0.90 | PPARA (0.60) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL13983694 | 0.88 | PPARA (0.59) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL9372364 | 0.84 | PPARA (0.72) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL10867374 | 0.84 | PPARA (0.72) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| Clofibric Acid SCHEMBL2227936 | 0.84 | PPARA (1.00) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| Clofibric Acid SCHEMBL102826 | 0.84 | PPARA (1.00) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL9590123 | 0.84 | PPARA (0.52) | PPARACYP1A2CYP3A4CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE48164-E1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES INC. (US) | 2020-08-18 | — | — | US | disclosed |
| US-10647673-B2 | Acetophenone compound, preparation method thereof, and application thereof in fatty liver prevention and treatment | Nanjing Bioenergy Medicine Science & Technology Co., Ltd. (CN) | 2020-05-12 | — | — | US | disclosed |
| US-20190292153-A1 | Acetophenone Compound, Preparation Method Thereof, And Application Thereof In Fatty Liver Prevention And Treatment | Nanjing Bioenergy Medicine Science & Technology Co., Ltd. (CN) | 2019-09-26 | — | — | US | disclosed |
| EP-2057112-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2018-12-19 | — | — | EP | disclosed |
| EP-2269977-B1 | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme | ABBVIE INC (US) | 2016-04-27 | — | — | EP | disclosed |
| US-9290444-B2 | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme | ABBVIE INC. (US) | 2016-03-22 | — | — | US | disclosed |
| EP-2257524-B1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | BRICKELL BIOTECH INC (US) | 2016-01-06 | — | — | EP | disclosed |
| EP-2257524-B1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | BRICKELL BIOTECH INC (US) | 2016-01-06 | — | — | EP | disclosed |
| US-20150065508-A1 | INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME | ABBVIE INC. (US) | 2015-03-05 | — | — | US | disclosed |
| US-8895777-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES INC (US) | 2014-11-25 | — | — | US | disclosed |
| US-4166861-A | ESTERS OF CATECHIN AND EPICATECHIN; ANTILIPEMIC, ANTICHOLESTEROL, HEPATOPROTECTIVE | INVERNI DELLA BEFFA S.P.A. (IT) | 1979-09-04 | — | — | US | disclosed |
| US-4151303-A | Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions | BOEHRINGER MANNHEIM GMBH (DE) | 1979-04-24 | — | — | US | disclosed |
| US-4146637-A | ANTIALLERGENS | LUDWIG MERCKLE K.G., CHEM. PHARM. FABRIK (DE) | 1979-03-27 | — | — | US | disclosed |
| US-4140770-A | Benzoylethers and processes for their production | A. NATTERMANN & CIE. GMBH (DE) | 1979-02-20 | — | — | US | disclosed |
| US-4118583-A | ANTICOAGULANT, ANTICHOLINERGIC AGENTS | LABORATORIES OM SOCIETE ANONYME (CH) | 1978-10-03 | — | — | US | disclosed |
| US-4115648-A | HYPOCHOLESTEROLEMIC, HYPOTRIGLYCIDEMIC, HYPOLIPIDEMIC | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1978-09-19 | — | — | US | disclosed |
| US-4017530-A | ANALGESIC, ANTICHOLESTEROL, ANTILIPEMIC | BLUM JEAN | 1977-04-12 | — | — | US | disclosed |
| US-4001447-A | HAVING HYPOLIPEMIANT, VASODILATATORY AND HYPOCHOLESTEROLEMIANT ACTIVITIES | ROUSSEL-UCLAF (FR) | 1977-01-04 | — | — | US | disclosed |
| US-3987175-A | ATHEROSCLEROSIS | PIERRE FABRE S.A. (FR) | 1976-10-19 | — | — | US | disclosed |
| US-3954767-A | HYPOCHOLESTEROLEMIC, HYPOTRIGLYCIDEMIC AND HYPOLIPIDEMIC ACTIVITY | PROVESAN SA, 19, RUE DE LA CROIX D'OR, GENEVA, SWITZERLAND, A SWISS CORP. | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065508-A1 | INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME | HSD11B1, HSD11B2, HSD17B1 | PPARA 2462/4885CYP1A2 166/4885CYP3A4 430/4885 |
| US-10647673-B2 | Acetophenone compound, preparation method thereof, and application thereof in fatty liver prevention and treatment | LIPC, CYP27A1, HSD17B10 | PPARA 14/4885CYP1A2 167/4885CYP3A4 283/4885 |
| US-20190292153-A1 | Acetophenone Compound, Preparation Method Thereof, And Application Thereof In Fatty Liver Prevention And Treatment | LIPC, CYP27A1, HSD17B10 | PPARA 14/4885CYP1A2 167/4885CYP3A4 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.