Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539809 | 0.97 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3SIGMAR1TMEM97 | |
| SCHEMBL11539814 | 0.97 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3SIGMAR1TMEM97 | |
| SCHEMBL11242548 | 0.96 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3SIGMAR1TMEM97 | |
| SCHEMBL11553404 | 0.89 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3SIGMAR1MEN1 | |
| SCHEMBL11548467 | 0.89 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3SIGMAR1MEN1 | |
| SCHEMBL11548463 | 0.89 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3SIGMAR1MEN1 | |
| Bromide SCHEMBL11547860 | 0.89 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3SIGMAR1MEN1 | |
| Bromide SCHEMBL11547863 | 0.89 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3SIGMAR1MEN1 | |
| SCHEMBL11551635 | 0.87 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3SIGMAR1MEN1 | |
| SCHEMBL11547501 | 0.86 | CYP1A2 (0.51) | SLC6A4SLC6A2SLC6A3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141893-A | Decahydrocyclopent[c]azepines | ELI LILLY AND COMPANY (US) | 1979-02-27 | — | — | US | claimed |