Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551237 | 0.96 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3SIGMAR1ALDH1A1 | |
| SCHEMBL11539809 | 0.93 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3SIGMAR1ALDH1A1 | |
| SCHEMBL11539814 | 0.93 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3SIGMAR1ALDH1A1 | |
| SCHEMBL11241096 | 0.89 | OPRM1 (0.46) | SLC6A4SLC6A2SLC6A3SIGMAR1ALDH1A1 | |
| SCHEMBL11539150 | 0.88 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3SIGMAR1ALDH1A1 | |
| SCHEMBL11539155 | 0.88 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3SIGMAR1ALDH1A1 | |
| SCHEMBL11536050 | 0.86 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3SIGMAR1OPRM1 | |
| SCHEMBL11194103 | 0.86 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3SIGMAR1OPRM1 | |
| SCHEMBL11194100 | 0.86 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3SIGMAR1OPRM1 | |
| SCHEMBL11243848 | 0.86 | OPRM1 (0.49) | SLC6A4SLC6A2SLC6A3SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337341-A | 4a-Aryl-octahydro-1H-2-pyrindines | ELI LILLY AND COMPANY (US) | 1982-06-29 | — | — | US | disclosed |