Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11848148 | 0.91 | NOTUM (0.46) | SMN1; SMN2NOTUMALDH1A1MAPTHPGD | |
| SCHEMBL27465095 | 0.91 | SMN1; SMN2 (0.57) | SMN1; SMN2NOTUMALDH1A1HTTMAPT | |
| SCHEMBL4688756 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2NOTUMALDH1A1HTTMAPT | |
| SCHEMBL6995452 | 0.81 | NOTUM (0.59) | SMN1; SMN2NOTUMALDH1A1HTTMAPT | |
| SCHEMBL20869536 | 0.79 | NOTUM (0.53) | SMN1; SMN2NOTUMALDH1A1HTTMAPT | |
| SCHEMBL29997798 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2NOTUMALDH1A1HTTMAPT | |
| SCHEMBL8471853 | 0.75 | NOTUM (0.49) | SMN1; SMN2NOTUMALDH1A1MAPTHPGD | |
| SCHEMBL29092593 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2NOTUMALDH1A1HTTMAPT | |
| SCHEMBL11551817 | 0.73 | SMN1; SMN2 (0.81) | SMN1; SMN2NOTUMALDH1A1HTTMAPT | |
| SCHEMBL330273 | 0.72 | SMN1; SMN2 (0.74) | SMN1; SMN2NOTUMALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151282-A | USING 5,6-DIHYDRO-4H-PYRROLO(3,2,1-IJ)QUINOLINE-1,2-DIONE | A. H. ROBINS COMPANY, INC. (US) | 1979-04-24 | — | — | US | disclosed |