Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Ethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylamine SCHEMBL28257747 | 1.00 | — | — | |
| Ethylamine SCHEMBL31272398 | 1.00 | — | — | |
| Ethylamine SCHEMBL28257748 | 1.00 | DNM1 (0.33) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Ethylamine SCHEMBL1534942 | 1.00 | — | — | |
| Ethylamine SCHEMBL22206634 | 0.94 | — | — | |
| Ethylamine SCHEMBL19253823 | 0.94 | — | — | |
| Ethylamine SCHEMBL1793 | 0.93 | — | — | |
| Ethylamine SCHEMBL1331327 | 0.93 | — | — | |
| Ethylamine SCHEMBL854887 | 0.93 | — | — | |
| Ethylamine SCHEMBL18835208 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147699-A | β-Lactam precursors of penicillin and cephalosporin antibiotics | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1979-04-03 | — | — | US | disclosed |