Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29533227 | 0.88 | KDM4E (0.56) | KDM4EGAALMNAPDE3BPDE3A | |
| SCHEMBL3319211 | 0.88 | KDM4E (0.56) | KDM4EGAALMNAPDE3BPDE3A | |
| SCHEMBL27057151 | 0.79 | TRPV1 (0.52) | ENPP1KDM4EGAALMNATRPV1 | |
| SCHEMBL3427577 | 0.77 | KDM4E (0.45) | KDM4EGAALMNATRPV1PDE3B | |
| SCHEMBL11556425 | 0.76 | ENPP1 (0.68) | ENPP1KDM4EALDH1A1HTTEHMT2 | |
| SCHEMBL29736340 | 0.74 | KDM4E (0.58) | KDM4EGAALMNATRPV1PDE3B | |
| SCHEMBL28753716 | 0.74 | KDM4E (0.58) | KDM4EGAALMNATRPV1PDE3B | |
| SCHEMBL27167377 | 0.74 | KDM4E (0.72) | KDM4EGAALMNAPDE3BPDE3A | |
| SCHEMBL11555624 | 0.73 | ALDH1A1 (0.74) | ENPP1KDM4EGAAPDE3BPDE3A | |
| SCHEMBL29900596 | 0.72 | KDM4E (0.67) | KDM4EGAALMNAPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141979-A | Tetrazolo[a]quinazol-5-ones antiallergy and antiulcer agents | PFIZER INC. (US) | 1979-02-27 | — | — | US | disclosed |
| US-4085213-A | Tetrazolo[A]quinazol-5-ones antiallergy and antiulcer agents | PFIZER INC. (US) | 1978-04-18 | — | — | US | disclosed |