Toluene

Toluene

SCHEMBL115541

CC(C)=O.Cc1ccccc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.69
TSHR P16473 1/20 0.69
ALOX12 P18054 1/20 0.69
ACHE P22303 1/20 0.69
CES2 O00748 3/20 0.56
CES1 P23141 3/20 0.56
SMN1; SMN2 Q16637 5/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
MAPT P10636 2/20 0.46
AKR1C3 P42330 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
HSD17B10 Q99714 1/20 0.46
POLB P06746 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
SRD5A2 P31213 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL27411160 1.00 LMNA (0.69) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL4662740 1.00 LMNA (0.69) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL27482878 1.00 LMNA (0.69) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL9815765 1.00 LMNA (0.69) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL10941235 1.00 LMNA (0.69) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL9176449 1.00 LMNA (0.69) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL5776784 1.00 LMNA (0.69) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL9689391 1.00 LMNA (0.69) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL19715122 1.00 LMNA (0.69) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL10604374 1.00 LMNA (0.69) LMNATSHRALOX12ACHECES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023067617-A1 A PROCESS FOR THE PREPARATION OF TETRAHYDROANTHRACENES FROM STREPTOMYCES SPP. AND ANTICANCER ACTIVITY THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2023-04-27 WO claimed
EP-2686366-B1 BIO-BASED POLYESTER LATEX OCE TECH BV (NL) 2019-12-25 EP claimed
CN-110246641-A A method of preparing the hyaluronic acid decorated Superparamagnetic Iron Oxide nanoparticle of the degradation of good dispersion 桂林理工大学 2019-09-17 CN claimed
CN-110201179-A A kind of preparation method of the ferric oxide nano particles for the chondroitin sulfate modification that can be distributed in intracerebral space between cells 桂林理工大学 2019-09-06 CN claimed
CN-110092964-A A kind of preparation method of polyvinyl high thermal conductivity composite plastic 广州市白云区钟落潭家立美塑料制品厂 2019-08-06 CN claimed
CN-109395427-A A kind of environment-friendly type glabridin extraction element and its technique 湖州欧利生物科技有限公司 2019-03-01 CN claimed
CN-109374815-A A kind of quality determining method for treating cough and asthma fullness sensation in chest pharmaceutical composition 贵州大隆药业有限责任公司 2019-02-22 CN claimed
CN-108912069-A A kind of Vortioxetine and C2-C4New salt form of dicarboxylic acids and the preparation method and application thereof 梧州学院 2018-11-30 CN claimed
US-10072163-B2 Intumescent coating composition PPG COATINGS EUROPE BV (NL) 2018-09-11 US claimed
CN-107248583-A Polybenzimidazoles poly ion liquid is crosslinked compound high temperature proton exchange film and preparation method thereof 长春工业大学 2017-10-13 CN claimed
EP-0828501-B1 EXTRACT FROM THE LEAVES OF GINKGO BILOBA MONTANA LTD (IE) 2004-09-29 EP claimed
US-6706192-B2 SUBJECTING CYCLOSPORIN COMPLEX TO MULTISTEP SILICA GEL COLUMN CHROMATOGRAPHY IN WHICH THE MOBILE PHASE IS A SOLVENT COMPRISING TOLUENE AS THE MAIN COMPONENT BIOGAL GYOGYSZERGYAR RT. (HU) 2004-03-16 US claimed
US-6423233-B1 COLUMN USED FOR MULTISTEP CHROMATOGRAPHY AND AND FILLED WITH SILICA AND A SOLVENT MIXTURE CONTAINING TOLUENE; CYCLOSPORIN A FROM A CRUDE PRODUCT OF CYCLOSPORIN COMPLEX BIOGAL GYOGYSZERGYAR RT. (HU) 2002-07-23 US claimed
CN-1280995-A Trapezoidal polysiloxane containing organic bridge radical and its preparing process CHINESE ACAD INST CHEMISTRY (CN) 2001-01-24 CN claimed
EP-0828501-A1 EXTRACT FROM THE LEAVES OF GINKGO BILOBA MONTANA LIMITED (IE) 1998-03-18 EP claimed
US-5688864-A SURFACE MODIFIED WITH REACTION WITH FLUOROALKYLSILANE IN SOLVENT PPG INDUSTRIES, INC. (US) 1997-11-18 US claimed
WO-1996038160-A1 EXTRACT FROM THE LEAVES OF GINKGO BILOBA MONTANA LIMITED (IE) 1996-12-05 WO claimed
US-4447529-A IMMUNOASSAY; AMINOGLYCOSIDE ANTIBIOTICS; STRIPS MILES LABORATORIES, INC. (US) 1984-05-08 US claimed
WO-1980000131-A1 MAGNETIC SEPARATION PROCESS FOR BENEFICIATING SULFIDE ORES HAZEN RESEARCH (US) 1980-02-07 WO claimed
US-4012553-A UNSATURATED POLYESTER, COPOLYMERIZABLE MONOMER AND ACYLOIN PHOTOINITIATOR; GELATINIZED, RADIATION-CURABLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-03-15 US claimed