Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11847493 | 0.89 | MEN1 (0.57) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL11551932 | 0.85 | MEN1 (0.65) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL11902017 | 0.84 | L3MBTL1 (0.48) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL3262977 | 0.82 | MEN1 (0.53) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL15953535 | 0.82 | MEN1 (0.52) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL6796833 | 0.81 | MEN1 (0.52) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL29241859 | 0.80 | MAPT (0.68) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL6799629 | 0.80 | MAPT (0.56) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL2503337 | 0.79 | MAPT (0.59) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL4064354 | 0.79 | EPAS1 (0.59) | MEN1KMT2AL3MBTL1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144341-A | ANTIPYRETICS, ANALGESICS AND ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4000286-A | ANALGESICS, ANTIINFLAMMATORY AND ANTIPYRETIC AGENTS | MERCK & CO., INC. (US) | 1976-12-28 | — | — | US | disclosed |