Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.53 |
| ▸ | CCR5 | P51681 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604480 | 0.84 | MCHR1 (0.54) | USP30MCHR1HRH3KCNH2 | |
| SCHEMBL2637307 | 0.83 | MCHR1 (0.49) | MCHR1NOTUMNPY5R | |
| SCHEMBL1749695 | 0.83 | MCHR1 (0.49) | MCHR1NOTUMNPY5R | |
| SCHEMBL11559508 | 0.81 | DPP4 (0.44) | MCHR1NOTUM | |
| SCHEMBL1750857 | 0.80 | MCHR1 (0.58) | MCHR1HRH3 | |
| SCHEMBL1749414 | 0.80 | MCHR1 (0.58) | MCHR1HRH3 | |
| SCHEMBL1750259 | 0.80 | MCHR1 (0.58) | MCHR1HRH3 | |
| SCHEMBL1164100 | 0.77 | MCHR1 (0.50) | USP30MCHR1CCR5HRH3 | |
| SCHEMBL14320321 | 0.76 | ALDH1A1 (0.48) | USP30CCR5 | |
| SCHEMBL1750097 | 0.76 | MCHR1 (0.43) | MCHR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143150-A | ANTIALLERGENS | A. H. ROBINS COMPANY, INC. (US) | 1979-03-06 | — | — | US | disclosed |