Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 8/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10094249 | 0.81 | SYK (0.48) | SYKSMN1; SMN2BACE1BACE2PIK3CA | |
| SCHEMBL11562332 | 0.78 | MAPT (0.55) | SYKSMN1; SMN2 | |
| SCHEMBL7697294 | 0.75 | CA12 (0.47) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL7695744 | 0.74 | CA12 (0.68) | SYKCA12CA1CA2CA9 | |
| SCHEMBL30269611 | 0.74 | CLK1 (0.53) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL11557056 | 0.74 | CLK1 (0.53) | CA12CA1CA2CA9SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11554953 | 0.73 | CLK1 (0.52) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL19851118 | 0.71 | CA12 (0.63) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL1859867 | 0.71 | CA12 (0.63) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL6804491 | 0.71 | CA12 (0.51) | SYKCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144341-A | ANTIPYRETICS, ANALGESICS AND ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |