SCHEMBL11557056

SCHEMBL11557056

Nc1cccnc1Nc1ccc2c(c1)OCO2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CLK1 P49759 2/20 0.53
▸ ULK1 O75385 2/20 0.52
▸ NPC1 O15118 5/20 0.50
▸ RAB9A P51151 5/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ CA12 O43570 1/20 0.49
▸ CA1 P00915 1/20 0.49
▸ CA2 P00918 1/20 0.49
▸ CA9 Q16790 1/20 0.49
▸ TUBB4A P04350 7/20 0.47
▸ TUBB P07437 7/20 0.47
▸ TUBA3C P0DPH7 7/20 0.47
▸ TUBA1B P68363 7/20 0.47
▸ TUBA4A P68366 7/20 0.47
▸ TUBB4B P68371 7/20 0.47
▸ TUBB3 Q13509 7/20 0.47
▸ TUBB2A Q13885 7/20 0.47
▸ TUBB8 Q3ZCM7 7/20 0.47
▸ TUBA3E Q6PEY2 7/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30269611 1.00 CLK1 (0.53) CLK1ULK1NPC1RAB9AALOX15
Hydrochloric Acid SCHEMBL11554953 0.99 CLK1 (0.52) CLK1ULK1NPC1RAB9AALOX15
SCHEMBL11562202 0.79 RAB9A (0.42) CLK1NPC1RAB9AALOX15HSD17B10
SCHEMBL12172543 0.78 CLK1 (0.48) CLK1ULK1NPC1RAB9AALOX15
SCHEMBL11554855 0.78 MAPT (0.55) CLK1NPC1RAB9AALOX15HSD17B10
Hydrochloric Acid SCHEMBL11558741 0.77 PIK3CA (0.50) NPC1RAB9ACA12CA1CA2
SCHEMBL11559669 0.76 ULK1 (0.51) CLK1ULK1NPC1RAB9AALOX15
SCHEMBL11559242 0.76 ULK1 (0.54) CLK1ULK1NPC1RAB9AALOX15
SCHEMBL2782868 0.76 MAPK14 (0.54) NPC1RAB9AALOX15HSD17B10KDM4E
SCHEMBL6922840 0.76 EPHX2 (0.56) CLK1ULK1NPC1RAB9AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3936512-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS Universal Display Corporation (US) 2022-01-12 — — EP disclosed
EP-3424935-B1 IMIDAZOPYRAZINYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORP (US) 2021-08-11 — — EP disclosed
EP-3424935-B1 IMIDAZOPYRAZINYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORP (US) 2021-08-11 — — EP disclosed
US-20210050530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 — — US disclosed
US-10873038-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-12-22 — — US disclosed
US-20190109287-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-04-11 — — US disclosed
EP-3424935-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS Universal Display Corporation (US) 2019-01-09 — — EP disclosed
US-9972793-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-05-15 — — US disclosed
US-9972793-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-05-15 — — US disclosed
US-20150021590-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-01-22 — — US disclosed
US-20150021590-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-01-22 — — US disclosed
US-8883322-B2 Pyridyl carbene phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2014-11-11 — — US disclosed
US-8883322-B2 Pyridyl carbene phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2014-11-11 — — US disclosed
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2012-09-13 — — US disclosed
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2012-09-13 — — US disclosed
US-4144341-A ANTIPYRETICS, ANALGESICS AND ANTIINFLAMMATORY AGENTS MERCK & CO., INC. (US) 1979-03-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210050530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NUDC, NCL, NDC1 CLK1 1486/4885ULK1 854/4885NPC1 3431/4885
US-10873038-B2 Organic electroluminescent materials and devices NUDC, NCL, NDC1 CLK1 1486/4885ULK1 854/4885NPC1 3431/4885
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS PAICS, PIR, NUDC CLK1 1117/4885ULK1 922/4885NPC1 3236/4885
US-20190109287-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NUDC, NCL, NDC1 CLK1 1486/4885ULK1 854/4885NPC1 3431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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